抽象的

Cydonia oblonga ????????????????? PI3K/AKT ?????????????

唐丹、謝連珍、辛雪蕾、HA Aisa

???????????????????????????Cydonia oblonga Miller?????????????????????????????????C. oblonga Mill???????????????CSE???????

????? CSE ? L6 ??????????????????????

???????CSE??????????1B?PTP1B??????? L6 ????????????? CSE?0 μg/ml ? 100 μg/ml??? 1 ???? MTT ???????????? L6 ?????????? (LDH) ?????????????????? PI3K/AKT ??????????????IRS-1?AKT?GSK-3β ? AMPK????????

??? CSE??????PTP1B???IC50??3.5 μg/mL?? CSE?0 μg/ml ? 100 μg/ml??? L6 ?????????????? 12.5 μg/ml ? CSE ??? L6 ?????????????? Western blotting?????CSE????????IRS-1?AKT?GSK-3β???????

????????????CSE????L6????PI3K/AKT?????????????????????????????CSE????????????????????????????