抽象的

??????????????????

Bradley S Jermy 1,2*、Kylie P Glanville1、Jonathan RI Coleman1,2、Cathryn M Lewis1,2,3、Evangelos Vassos1,2

??????? (MDD) ????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????? MDD ??????????????

????????????????????? 32 ?????? MDDbull ??????????????SNP ?????????????????????????????????????(PGC) ???????23andMe, Inc. ?????????????????????????????

???????????h2 SNP ???0.102–0.162?????????????????????????Rg ???0.651–0.894 (PGC)?0.652–0.837 (23andMe) ?0.699–0.900????????? 5 ?????????????????????? SNP ????????????????????????? 1.4%????? 2.7%??????????????????

??????????????????????????????????????? MDD ?????????????????????????????????????????????????????????????