曹輝、蘇文龍、李俊傑、溫冰強、田淑君、孫樹春、李璐、王漢陽、李傑新
???????????????????? (HDACi) ????????? (SCNT) ???????????????? Scriptaid????? HDACi????????????????????????????????????????????0?0.1?0.2?0.4 ? 0.8 μmol/L????????0?12?24?36 ? 48 ????????????????? Scriptaid ??????????????????????????? SCNT ?????? H3 ??? 9 (acH3K9) ???? H4 ??? 12 (acH4K12) ???????????????????????G0/G1???????????????????(0.2 μmol/L) Scriptaid ???24 ????????????????????????????21/86 [24.39%] ?11/85 [12.91 %]?? P<0.05??????????SCNT???acH3K9?acH4K12?????????P<0.05??????????????Scriptaid??????????G0/G1???????84.22% vs. 75.96%?P<0.05??????Scriptaid????????????SCNT????????????????acH3K9/ acH4K12?G0/G1??????? Scriptaid ?????????????????
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