Moin Shakeb、SB Puranik和Swamy Sreenivasa
?????????????? ICH ??????????????????????????????????????????????HPLC ?? LC Shimadzu UFLC-2000 Prominance LC- 20AD ???????SPDM 20A ?????? Rheodyne ???? EnableC18 G ??? 250x 4.6mm?5μm????? 20μL???????????? 50mM ?????? (70:30% v/v) ?????????? 235 nm ??? PDA ?????????????? 150-350μg/ml?r2 = 0.999????????????????????? 0.019 ? 0.053μg/ml??????????? 15-35μg/ml?r2 = 0.999???????????? 0.023 ? 0.070μg/ml???????????????????????????????????????