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In Vitro Free Radical Scavenging and Membrane Stabilizing Activity of Paederia foetida Leaves

Riaz Uddin, Raushanara Akter, SM Raquibu Hasan, Ehsanu Hoque Mazumder, and Md Ashraful Alam

Paederia foetida is a native Bangladeshi plant, used for the treatments of various diseases in folklore medicine. In this study, the antioxidant potential of Paederia foetida extract was evaluated by using a series of well established antioxidant assay systems. Paederia foetida extract scavenge DPPH radical in a dose dependent manner. The extract was also showed potent free radicals inhibitory activity generated from sodium nitroprusside as nitric oxide and free radicals from H2O2. Furthermore, Paederia foetida extract showed moderate reducing power and potent membrane stabilizing activity of RBC membrane in hypotonic medium. The extracts exhibited remarkable antioxidant activities in all system studied. Scavenging of reactive oxygen species (ROS) may be attributed to the high amount of phenolic compounds present in the extract. Further study is necessary for isolation and characterization of the antioxidants present in the extract, which may serve as a potential source of natural healer for oxidative stress and inflammatory diseases.

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谷歌学术
打开 J 门
研究圣经
引用因子
宇宙IF
开放学术期刊索引 (OAJI)
学者指导
普布隆斯
国际创新期刊影响因子(IIJIF)
国际组织研究所 (I2OR)
宇宙
日内瓦医学教育与研究基金会
秘密搜索引擎实验室
欧洲酒吧

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