Wifaq M.Ali Al-Wattar
Background: Oral candidiasis is a mycosis (yeast/fungal infection) of Candida species on the mucous membranes of the mouth. Humeral immune response to candidal infection has much theory according to site of infection mediated by T-helper maturation, differentiation and secretion of cytokines. Interleukin-33 is one of the IL-1 super families which are called alarming cytokines family as they inform the immune system about any tissue injury, infection or necrosis. IL-33 is multifunctional cytokines that has anti-inflammatory (protective), inflammatory effect on tissue by modulating the action of T-Helper17. Aim of study: To study the effect of InterLeukin-33 on T-Helper 17 cytokines InterLeukin-17 and InterLeukin-22 in saliva of patients with oropharyngeal candidiasis before and after therapy with Nystatine in comparison to control.
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