抽象的

A Review: Polymeric In-situ Gel System

Jaya Raja Kumar K, Selvadurai Muralidharan and Sokkalingam Arumugam Dhanaraj

Smart polymeric systems represent promising means of delivering the drugs; these polymers undergo sol-gel transition, once administered. In-situ gel structure occurs due to one or combination of different stimuli like pH change, temperature modulation and ionic exchange. The formation of gels depends on factors like temperature modulation, pH change, presence of ions and ultra violet irradiation, from which the drug gets released in a sustained and controlled manner. Mainly In-situ gels are administered by oral, ocular, rectal, vaginal, injectable and intraperitoneal routes. The In-situ gel forming polymeric formulations offer several advantages like sustained and prolonged action in comparison to conventional drug delivery systems. The article presents a detailed review of these types of polymeric systems, their evaluation, advancements and their commercial formulations. From a manufacturing point of view, the production of such devices is less complex and thus lowers the investment and manufacturing cost.

索引于

化学文摘社 (CAS)
哥白尼索引
打开 J 门
学术钥匙
研究圣经
引用因子
电子期刊图书馆
参考搜索
哈姆达大学
学者指导
国际创新期刊影响因子(IIJIF)
国际组织研究所 (I2OR)
宇宙
日内瓦医学教育与研究基金会
秘密搜索引擎实验室

查看更多