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LOW BODY MASS INDEX AND LOW SERUM ALBUMIN LEVEL AS RISK FACTORS FOR CARBON DIOXIDE RETENTION DURING ACUTE EXACERBATION OF CHRONIC OBSTRUCTIVE PULMONARY DISEASE

Vishnu Sharma M, Anupama N, Harsha D S, Viswambhar, AlakaChaitra Bhat, Basavaraj S, Rahul Antony Simon

This study was done to compare BMI and serum albumin level as risk factors for carbon dioxide retention during acute exacerbation of COPD. It was a hospital based case control study done on 60 male patients aged of 40- 80yrs already diagnosed as COPD as per GOLD 2010 guidelines. All patients with Paco2 level >46 mmHg which was not a compensation for metabolic alkalosis were classified as cases and those with Paco2 level <46 mmHg were controls. BMI and Serum albumin levels were compared between the two groups. Data was analysed by calculating odds ratio. The study shows that patients with low BMI showed 20 times risk of having carbon dioxide retention that of normal BMI patients and patients with low albumin levels showed a risk of having carbon dioxide retention 46 times that of patient with normal albumin