王宏毅、奚阳、陈媛媛、王璐艳、杨范、路熙宁、孙宁玲*
?????????????????????????AT1????????????????????????????
????2016?9?9??2018?12?7????44???????18?75???????BMI ?18.5 kg/m 2 ≤BMI≤30 kg/m 2?????SBP?140 mmHg≤<180 mmHg?????DBP?90 mmHg≤<110 mmHg????????EH????????????????240 mg????4?????????????8????????????1?1??????????????240 mg?+????????1.5 mg??A+D?????????+?????????5 mg??A+C?????8??????????12?????????????????4???8????????????????????????????
?????????2126??????12?????????????19.24±12.02?10.63±8.89 mmHg?????????78.56%???4?8??????????68.85%?79.99%?
????????4????????????????????12???????SBP/DBP???19.12±11.71/10.84±8.73 mmHg??p<0.0001??????4?8??????????A+D??A+C????????????????? 48????????????????????24 h?????133.29±11.56/80.46±10.19 mmHg???12??????????10.04±10.87/5.50±8.07 mmHg???????????????????????64.64%?62.63%????????3.82?2.92??????????7.26%?????????????96.15%???????????????
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